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Integration of metabolomics and proteomics analysis to explore the mechanism of neurotoxicity induced by receipt of isoniazid and rifampicin in mice

Xiaoyu Qu, Jie Ma, Huan Gao, Yueming Zhang, Jinghui Zhai, Jiawei Gong, Yanqing Song, Tingting Hu

2022NeuroToxicology11 citationsDOI

Topics & Concepts

NeurotoxicityPharmacologyMetabolomicsIsoniazidRifampicinBiochemistryMetabolismChemistryMetabolism disorderLipid metabolismPeroxisome proliferator-activated receptorPhenylalanineMetabolic pathwayBiologyAmino acidEndocrinologyMedicineToxicityReceptorAntibioticsTuberculosisPathologyOrganic chemistryChromatographyMetabolomics and Mass Spectrometry StudiesTryptophan and brain disordersPharmacological Receptor Mechanisms and Effects
Integration of metabolomics and proteomics analysis to explore the mechanism of neurotoxicity induced by receipt of isoniazid and rifampicin in mice | Litcius