Heterologous prime-boost vaccination against COVID-19: is it safe and reliable?
Om Prakash Choudhary, Priyanka Choudhary, Jivan Qasim Ahmed, Teroj A. Mohammed, Indraj Singh, Alfonso J. Rodríguez‐Morales
Abstract
Throughout the globe, many nations are struggling to cope with the consecutive waves of the COVID-19. Several vaccines have been employed to overcome this ongoing pandemic and are available as single and double-dose inoculations; however, homologous vaccine efficacy is being reconsidered due to the rapidly emerging SARS-CoV-2 variants. Many studies have been conducted on the heterologous prime-boost vaccine regimens and have shown good efficacy results against COVID-19. This article aims to highlight the safety and reliability of heterologous prime-boost vaccination against COVID-19. We have also made some recommendations towards using these combinations of vaccines for the global mitigation of the subsequent waves of COVID-19.