Organs-on-chips: a decade of innovation
Carly Strelez, Hannah Y. Jiang, Shannon M. Mumenthaler
Abstract
Recreating 'living organs' with groundbreaking organ-on-a-chip (OOC) technologies is facilitating a new era of drug discovery. Studies by Huh et al. and Ronaldson-Bouchard et al. underscore advances made over a decade, spanning single organ functionality to interconnected organs, that enable examination of drug toxicities and disease pathogenesis in reconstituted tissues.
Topics & Concepts
Drug discoveryDiseaseBiologyPathogenesisComputational biologyEngineering ethicsMedicineBioinformaticsEngineeringPathologyImmunology3D Printing in Biomedical ResearchInnovative Microfluidic and Catalytic Techniques InnovationNeuroscience and Neural Engineering