Litcius/Paper detail

FDA approval summary for lonafarnib (Zokinvy) for the treatment of Hutchinson-Gilford progeria syndrome and processing-deficient progeroid laminopathies

Mari Suzuki, Linda Jo Bone Jeng, Solomon Chefo, Yan Wang, Dionne Price, Xiaohui Li, Jie Wang, Ruo‐Jing Li, Lian Ma, Yuching Yang, Xinyuan Zhang, Nan Zheng, Ke Zhang, David B. Joseph, Hitesh N. Shroff, Jenny Doan, Michael Pacanowski, Patroula Smpokou, Kathleen Donohue, Hylton V. Joffe

2022Genetics in Medicine51 citationsDOIOpen Access PDF

Topics & Concepts

ProgeriaFood and drug administrationMedicineOrphan drugDrugPharmacologyBioinformaticsGeneticsBiologyGeneNuclear Structure and FunctionDNA Repair MechanismsPARP inhibition in cancer therapy