Seeding the idea of encapsulating a representative synthetic metagenome in a single yeast cell
Ignacio Belda, Thomas C. Williams, Miguel de Celis, Ian T. Paulsen, Isak S. Pretorius
Abstract
Synthetic metagenomics could potentially unravel the complexities of microbial ecosystems by revealing the simplicity of microbial communities captured in a single cell. Conceptionally, a yeast cell carrying a representative synthetic metagenome could uncover the complexity of multi-species interactions, illustrated here with wine ferments.
Topics & Concepts
MetagenomicsYeastComputational biologySynthetic biologyBiologySingle-cell analysisYeast in winemakingCellSaccharomyces cerevisiaeGeneGeneticsMicrobial Metabolic Engineering and BioproductionBioinformatics and Genomic NetworksFermentation and Sensory Analysis