2-Deoxyglucose drives plasticity via an adaptive ER stress-ATF4 pathway and elicits stroke recovery and Alzheimer’s resilience
Amit Kumar, Saravanan S. Karuppagounder, Yingxin Chen, Carlo Corona, Riki Kawaguchi, Yuyan Cheng, Mustafa Balkaya, Botir T. Sagdullaev, Zhexing Wen, Charles Stuart, Sunghee Cho, Guo‐li Ming, Jürgen Tuvikene, Tõnis Timmusk, Daniel H. Geschwind, Rajiv R. Ratan
Topics & Concepts
ATF4NeuroplasticityProteostasisTranscription factorNeuroscienceUnfolded protein responseSynaptic plasticityDementiaEndocrinologyBiologyInternal medicineCell biologyMedicineGeneDiseaseBiochemistryEndoplasmic reticulumReceptorGenetics, Aging, and Longevity in Model OrganismsPancreatic function and diabetesDiet and metabolism studies