Molecular Targets of Oxidative Stress: Focus on the Nrf2 Signaling Pathway in Health and Disease
Marcel Bonay
Abstract
Oxidative stress, known to increase the risk of multiple metabolic and chronic disorders or cancer development, is defined as an imbalance between the production of reactive oxygen species (ROS) and the capacity of antioxidants to counteract the deleterious effects of oxidants [...].
Topics & Concepts
Oxidative stressReactive oxygen speciesDiseaseSignal transductionCell biologyOxidative phosphorylationChemistryBiologyBioinformaticsBiochemistryMedicineInternal medicineGenomics, phytochemicals, and oxidative stressGlutathione Transferases and PolymorphismsVitamin C and Antioxidants Research