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68Ga-FAPI and 18F-FDG PET/CT Images in a Patient With Extrapulmonary Tuberculosis Mimicking Malignant Tumor

Bingxin Gu, Zhiguo Luo, Xinhong He, Jian Wang, Shaoli Song

2020Clinical Nuclear Medicine65 citationsDOIOpen Access PDF

Abstract

Extrapulmonary tuberculosis (TB) is difficult to diagnose. Here, we report a case of extrapulmonary TB in a 68-year-old woman presented with mental fatigue, poor appetite, and weight loss. F-FDG PET/CT revealed elevated F-FDG uptake in the left inferior cervical, left supraclavicular, mediastinal, and splenic hilum lymph nodes and spleen, which were suspected of malignant tumor. To further differentiate benign and malignant diseases, Ga-FAPI PET/CT was performed. Ga-FAPI PET/CT also showed intense Ga-FAPI uptake in the previously mentioned FDG-avid lesions. However, biopsy of the left supraclavicular lymph node demonstrated the presence of TB.

Topics & Concepts

MedicineTuberculosisRadiologyBiopsyLymph nodeSpleenSupraclavicular lymph nodesHilum (anatomy)LymphPET-CTNuclear medicinePositron emission tomographyPathologyInternal medicineMetastasisCancerPeptidase Inhibition and AnalysisCardiac Structural Anomalies and RepairPneumocystis jirovecii pneumonia detection and treatment
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