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Single cell transcriptomics comes of age

Sarah Aldridge, Sarah A. Teichmann

2020Nature Communications374 citationsDOIOpen Access PDF

Abstract

Single cell transcriptomics technologies have vast potential in advancing our understanding of biology and disease. Here, Sarah Aldridge and Sarah Teichmann review the last decade of technological advancements in single-cell transcriptomics and highlight some of the recent discoveries enabled by this technology.

Topics & Concepts

TranscriptomeComputational biologyData scienceBiologyComputer scienceGeneticsGeneGene expressionSingle-cell and spatial transcriptomicsCytomegalovirus and herpesvirus researchExtracellular vesicles in disease