1,3-Difunctionalization of alkenes: state-of-the-art and future challenges
Dongkai Wang, Long Li, Qing Xu, Jianfeng Zhang, Hongxing Zheng, Wen‐Ting Wei
Abstract
This review summarizes the advances in 1,3-difunctionalization of alkenes mediated by Pd-, Ni-, Fe-, and Cu-based catalysts, as well as under metal-free conditions, with an emphasis on the reaction mechanisms and factors governing regioselectivity.
Topics & Concepts
ChemistryRegioselectivityCatalysisCombinatorial chemistryNanotechnologyOrganic chemistryMaterials scienceCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and Catalysis