Construction of a lysosome-targetable ratiometric fluorescent probe for H<sub>2</sub>O<sub>2</sub>tracing and imaging in living cells and an inflamed model
Rongrong Zhou, Qiyao Peng, Dan Wan, Yu Chao, Yuan Zhang, Yi Hou, Quan Luo, Xiong Li, Shuihan Zhang, Lin Xie, Pinghua Ou, Yongbo Peng
Abstract
Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), an important reactive oxygen species (ROS) with unique destructive oxidation properties, can be produced in lysosomes to fight off pathogens.
Topics & Concepts
LysosomeFluorescenceTracingChemistryBiophysicsNanotechnologyComputer scienceMaterials scienceBiologyOpticsBiochemistryPhysicsEnzymeOperating systemMolecular Sensors and Ion DetectionSulfur Compounds in BiologyNitric Oxide and Endothelin Effects