Potential Crosstalk between Liver and Extra-liver Organs in Mouse Models of Acute Liver Injury
Yufan Zheng, Baiping Cui, Wenrui Sun, Sining Wang, Xu Huang, Han Gao, Fei Gao, Qian Cheng, Limin Lü, Yanpeng An, Xiaobo Li, Ning Sun
Abstract
. Our data indicated that different types of acute liver injury led to different transcriptomic changes within extra-liver organs. Integration of serum metabolomics and transcriptomics from multiple tissues can improve our understanding of acute liver injury and its effect on the other organs.
Topics & Concepts
CrosstalkLiver injuryMedicineBiologyInternal medicinePhysicsOpticsDrug-Induced Hepatotoxicity and ProtectionLiver physiology and pathologyLiver Disease Diagnosis and Treatment