Occult<i>Talaromyces marneffei</i>Infection Unveiled by the Novel Mp1p Antigen Detection Assay
Vo Trieu Ly, Nguyen Tat Thanh, Nguyen Thi Mai Thu, Jasper Fuk‐Woo Chan, Jeremy Day, John R. Perfect, Cao Ngoc Nga, Nguyễn Văn Vĩnh Châu, Thuy Le
Abstract
causes fatal invasive mycosis in Southeast Asia. Diagnosis by culture has limited sensitivity and can result in treatment delay. We describe the use of a novel Mp1p enzyme immunoassay (EIA) to identify blood culture-negative talaromycosis, subsequently confirmed by bone marrow cultures. This EIA has the potential to speed diagnosis, enabling early therapy initiation.
Topics & Concepts
MedicineOccultAntigenVirologyMicrobiologyImmunologyPathologyBiologyAlternative medicineFungal Infections and StudiesPlant-Microbe Interactions and ImmunityPlant Pathogens and Fungal Diseases