Integrated gut microbiome and metabolome analysis reveals the inhibition effect of <i>Lactobacillus plantarum</i> CBT against colorectal cancer
Yanyan Chen, Fei Fei, Lingling Ding, Shiyuan Wen, Caifang Ren, Aihua Gong
Abstract
2-succinyl-L-ornithine, and (5-L-glutamyl)-L-glutamate). Furthermore, the inhibitory effect of LP-CBT on colorectal cancer was further confirmed using the MC38 subcutaneous tumor model. Collectively, these findings offer compelling evidence supporting the potential of LP-CBT as a viable preventive strategy against CRC.
Topics & Concepts
MetabolomeLactobacillus plantarumColorectal cancerGut microbiomeMicrobiomeCarcinogenesisLactobacillusGut floraBiologyCancerMicrobiologyCancer researchMetabolomicsBioinformaticsBacteriaImmunologyGeneticsLactic acidGut microbiota and healthProbiotics and Fermented FoodsCancer Research and Treatments