Progressive Reinvention or Destination Lost? Half a Century of Cardiovascular Tissue Engineering
Peter Zilla, Manfred Deutsch, Deon Bezuidenhout, Neil H. Davies, Timothy Pennel
Abstract
generation of functional tissue in humans remained unheeded-the trans-anastomotic outgrowth stoppage of endothelium and the build-up of an impenetrable surface thrombus. To overcome this dead-lock, research focus needs to shift from a biologically possible tissue regeneration response to one that is feasible at the intended site and in the intended host environment of patients. Equipped with an impressive toolbox of modern biomaterials and deep insight into cues for facilitated healing, reconnecting to the "user needs" of patients would bring one of the most exciting concepts of cardiovascular medicine closer to clinical reality.
Topics & Concepts
EnthusiasmMedicineTissue engineeringHuman heartCardiologyPsychologyBiomedical engineeringSocial psychologyElectrospun Nanofibers in Biomedical ApplicationsTissue Engineering and Regenerative MedicineCardiac and Coronary Surgery Techniques