NHC‐Catalyzed Enantioselective Transformations Involving α‐Bromoenals
Fatemeh Doraghi, Mahmoud Ameli, Shirin Ansariashlaghi, Bagher Larijani, Mohammad Mahdavi
Abstract
α-Haloenals, especially, α-bromoenals considered as one of the important building blocks in organic synthesis. They can participate in various (3+2)-, (3+3)-, (3+4)-, and (2+4)-annulation reactions with other organic molecules in the presence of an NHC catalyst to produce enantioenriched carbo-, and heterocyclic compounds. Herein, we have described NHC-catalyzed enantioselective transformations of α-bromoenals in the synthesis of various heterocycles, and carbocycles, as well as acyclic organic compounds.
Topics & Concepts
Enantioselective synthesisAnnulationCatalysisChemistryOrganic synthesisCombinatorial chemistryOrganic chemistryOrganic moleculesOrganocatalysisMoleculeN-Heterocyclic Carbenes in Organic and Inorganic ChemistryCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization Methods