In vivo anti-inflammatory, anti-nociceptive, and in vitro antioxidant efficacy, and acute oral toxicity effects of the aqueous and methanolic stem bark extracts of Lonchocarpus eriocalyx (Harms.)
Gervason Moriasi, Anthony Muriithi Ireri, Elias Nelson, Mathew Piero Ngugi
Abstract
antioxidant efficacies of these extracts were attributed to antioxidant phytocompounds with diverse pharmacologic effects, especially through the amelioration of oxidative stress. Further studies on the anti-inflammatory, antinociceptive and antioxidant mechanism(s) and isolation and characterisation of responsible compounds are encouraged to spur the development of affordable, accessible, safe, and efficacious drugs.
Topics & Concepts
AntioxidantDPPHAcute toxicityChemistryOxidative stressLipid peroxidationPharmacologyIn vivoTraditional medicineToxicityMedicineBiochemistryBiotechnologyBiologyOrganic chemistryEthnobotanical and Medicinal Plants StudiesBioactive natural compoundsNatural Antidiabetic Agents Studies