Agrimonia pilosa Ledeb.: A review of its traditional uses, botany, phytochemistry, pharmacology, and toxicology
Sihua Wen, Xiaofei Zhang, Ya-Nan Wu, Shangshang Yu, Wei Zhang, Ding Liu, Kai Yang, Jing Sun
Abstract
Ethnopharmacological relevance: Ledeb. is a herbal medicine with great scope for development and use. It is astringent and hemostatic, and it is used for treating malaria, preventing dysentery, detoxification, and as a tonic for deficiency. Aim of the review: Ledeb. and discuss the future research trends and development prospects of this plant. Materials and methods: Ledeb. was gathered via the Internet (China National Knowledge Infrastructure, Google Scholar, PubMed, Web of Science, SpringerLink, Wiley, Wanfang Data, and Baidu Academic). Additional information was obtained from books (Ben Cao Tu Jing, A Textual Research on the Name and Reality of Plants, Modern Practical Chinese Medicine, Zhen Nan Ben Cao) and PhD and MS dissertations. Results: Ledeb. show various pharmacological activities, including anti-inflammatory, anticancer, antitumor effects, antioxidant, analgesic effects, and other pharmacological effects. Conclusion: Ledeb. should be deepened, especially through clinical trials, to ensure the clinical safety of its use for further research.