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Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer

Elham Ahanin, Rebecca Sager, Sarah J. Backe, Diana M. Dunn, Natela Dushukyan, Adam R. Blanden, Nilamber A. Mate, Tamie Suzuki, Tyler Anderson, Merin Vellooparambil Roy, Jasmeen Oberoi, Chrisostomos Prodromou, Imad Nsouli, Michael Daneshvar, Gennady Bratslavsky, Mark R. Woodford, Dimitra Bourboulia, John D. Chisholm, Mehdi Mollapour

2023Cell chemical biology12 citationsDOIOpen Access PDF

Topics & Concepts

FADDPhosphataseRIPK1Cancer researchApoptosisEffectorBiologyCancerCell biologySignal transductionPhosphorylationBiochemistryCaspaseProgrammed cell deathGeneticsNecroptosisATP Synthase and ATPases ResearchCell death mechanisms and regulationHeat shock proteins research
Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer | Litcius