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A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity

Giorgia Palano, Maria Jansson, Anna Backmark, Stefan Martinsson, Alan Sabirsh, Kjell Hultenby, Peter Åkerblad, Kenneth L. Granberg, Karin Jennbacken, Erik Müllers, Emil M. Hansson

2020Journal of Molecular and Cellular Cardiology24 citationsDOI

Topics & Concepts

FibrosisCardiac fibrosisPhenotypeHigh-throughput screeningHeart failureMyocardial fibrosisIn vitroComputational biologyHigh-content screeningIdentification (biology)MedicineBiologyCancer researchBioinformaticsCellPathologyGeneCardiologyBiochemistryBotanyCardiac Fibrosis and RemodelingProtease and Inhibitor MechanismsTissue Engineering and Regenerative Medicine
A high-content, in vitro cardiac fibrosis assay for high-throughput, phenotypic identification of compounds with anti-fibrotic activity | Litcius