Visible-Light-Driven Decarboxylative Coupling of 2<i>H</i>-Indazoles with α-Keto Acids without Photocatalysts and Oxidants
Mengyu Niu, Chen Yang, Mingzhu Leng, Qun Cao, Meichao Li, Zhenlu Shen
Abstract
High Resolution Image Download MS PowerPoint Slide An efficient synthesis of functionalized 3-acyl-2 H -indazoles via visible-light-induced self-catalyzed energy transfer was developed. This method utilized a self-catalyzed energy transfer process between 2 H -indazoles and α-keto acids, offering advantages like absence of photosensitizers, metal catalysts, and strong oxidants, broad substrate compatibility, and operational simplicity under mild conditions.
Topics & Concepts
ChemistryCatalysisVisible spectrumDecarboxylationCombinatorial chemistrySubstrate (aquarium)Energy transferPhotochemistryOrganic chemistryOptoelectronicsGeologyMolecular physicsOceanographyPhysicsCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques