Cadmium-induced Carcinogenesis in Respiratory Organs and the Prostate: Insights from Three Perspectives on Toxicogenomic Approach
Jun Lee, Dong Yeop Shin, Yujin Jang, Jun Pyo Han, Eun-Min Cho, Young Rok Seo
Abstract
, leading to abnormal protein activities and maturation, suppressing tumor suppressors, and inducing apoptosis. Collectively, this review provides a comprehensive understanding of the carcinogenic mechanisms of Cd in two different organs by adopting toxicogenomic approaches. These insights can serve as a foundation for further research on cadmium-induced cancer, contributing to the establishment of future cancer prevention strategies.
Topics & Concepts
Prostate cancerCarcinogenesisCancer researchCarcinogenBiologyProstateCancerApoptosisAdverse Outcome PathwayBioinformaticsMedicineComputational biologyGeneticsHeavy Metal Exposure and ToxicityEpigenetics and DNA MethylationMercury impact and mitigation studies