Reduction of Carboxylic Acids to Alcohols via Manganese(I) Catalyzed Hydrosilylation
Emanuele Antico, Peter Schlichter, Christophe Werlé, Walter Leitner
Abstract
, the lowest amount of silane reported to date for this transformation. Kinetic data and control experiments have provided initial insight into the mechanism of the catalytic process, suggesting that it proceeds via the formation of silyl ester intermediates and ligand dissociation to generate a coordinatively unsaturated Mn(I) complex as the active species.
Topics & Concepts
HydrosilylationCatalysisManganeseChemistrySilaneSilylationCarboxylic acidDissociation (chemistry)MetalReducing agentLigand (biochemistry)SilanesCombinatorial chemistryOrganic chemistryReceptorBiochemistryAsymmetric Hydrogenation and CatalysisChemical Synthesis and ReactionsCarbon dioxide utilization in catalysis