Decarboxylation-triggered homo-Nazarov cyclization of cyclic enol carbonates catalyzed by rhenium complex
Natsuki Kimaru, Keiichi Komatsuki, Kodai Saito, Tohru Yamada
Abstract
Decarboxylative homo-Nazarov cyclization catalyzed by a Lewis acid was achieved using a cyclic enol carbonate bearing a cyclopropane moiety as a substrate. Various substrates were converted into the corresponding multi-substituted cyclohexenones in good yields via decarboxylation, followed by 6-membered ring formation involving cyclopropane-ring-opening.
Topics & Concepts
RheniumDecarboxylationEnolCatalysisChemistryPhotochemistryOrganic chemistryCyclopropane Reaction MechanismsCatalytic Alkyne ReactionsCatalytic C–H Functionalization Methods