Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases
Pierre Barennes, Valentin Quiniou, Mikhail Shugay, Evgeniy S. Egorov, Alexey N. Davydov, Dmitriy M. Chudakov, Imran Uddin, Mazlina Ismail, Theres Oakes, Benny Chain, Anne Eugster, Karl Kashofer, Peter P. Rainer, Samuel Darko, Amy Ransier, Daniel C. Douek, David Klatzmann, Encarnita Mariotti‐Ferrandiz
Topics & Concepts
T-cell receptorBiologyComputational biologyPolymerase chain reactionMultiplexRepertoireIn silicoMultiplex polymerase chain reactionDNAGeneticsMolecular biologyImmune systemT cellGenePhysicsAcousticsT-cell and B-cell ImmunologyImmune Cell Function and InteractionSingle-cell and spatial transcriptomics