Osthole inhibits GSK-3β/AMPK/mTOR pathway-controlled glycolysis and increases radiosensitivity of subcutaneous transplanted hepatocellular carcinoma in nude mice
Hui Huang, Jie Xue, Mei-Lin Xie, Tao Xie
Topics & Concepts
AMPKPI3K/AKT/mTOR pathwayMedicineGlycolysisProtein kinase ACancer researchGSK-3Glucose transporterInternal medicineGlycogenEndocrinologyAMP-activated protein kinaseKinaseSignal transductionBiologyMetabolismBiochemistryInsulinPlant chemical constituents analysisSesquiterpenes and Asteraceae StudiesPlant Toxicity and Pharmacological Properties