Druggable Lipid GPCRs: Past, Present, and Prospects
Hirotaka Mizuno, Yasuyuki Kihara
Topics & Concepts
G protein-coupled receptorDruggabilityLipid signalingDrug discoveryHeterotrimeric G proteinSphingosine kinaseComputational biologyReceptorPharmacologyBiologyChemistrySphingosineBiochemistryG proteinSphingosine-1-phosphateGeneReceptor Mechanisms and SignalingComputational Drug Discovery MethodsPharmacological Receptor Mechanisms and Effects