Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice
Jinbiao Chen, Ngan Ching Cheng, Jade A Boland, Ken Liu, James G. Kench, D. Neil Watkins, Sofía Ferreira-González, Stuart J. Forbes, Geoffrey W. McCaughan
Topics & Concepts
CiliumProgenitor cellPathologyPrimary biliary cirrhosisBiologyWnt signaling pathwayHepatocyteOrganoidStem cellCancer researchMedicineCell biologyImmunologyIn vitroSignal transductionBiochemistryGenetic and Kidney Cyst DiseasesLiver physiology and pathologyOrgan Transplantation Techniques and Outcomes