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Discovery of novel EGFR-PROTACs capable of degradation of multiple EGFR-mutated proteins

Yu Du, Shi Shi, Shu Chen, Yezi He, Wangyang Xu, Daochen Wu, Yushu Tian, Mingyang Kong, Jiahuan He, Wenhui Xie, Yijia Qiu, Yungen Xu, Yi Zou, Qihua Zhu, Qihua Zhu

2024European Journal of Medicinal Chemistry16 citationsDOI

Topics & Concepts

ChemistryDrug discoveryComputational biologyEGFR inhibitorsEpidermal growth factor receptorBiochemistryReceptorBiologyProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysPeptidase Inhibition and Analysis
Discovery of novel EGFR-PROTACs capable of degradation of multiple EGFR-mutated proteins | Litcius