PCB153 suppressed autophagy via PI3K/Akt/mTOR and RICTOR/Akt/mTOR signaling by the upregulation of microRNA-155 in rat primary chondrocytes
Ziyu Liu, Yue Huang, Xin Jin, Li Liu, Hailun Gu
Topics & Concepts
PI3K/AKT/mTOR pathwayDownregulation and upregulationProtein kinase BRPTORAutophagymTORC2microRNACell biologyChemistrySignal transductionCancer researchBiologymTORC1ApoptosisBiochemistryGeneAutophagy in Disease and TherapyCancer-related molecular mechanisms researchMicroRNA in disease regulation