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Off-label Use of Long-Acting Injectable Antiretroviral Therapy: A Single Center Retrospective Review of Youth Living With HIV With Detectable HIV RNA Starting Injectable Therapy

Alison Rousseau, Eric McGrath, Laura J. Benjamins, Salome Cockern, Jill Meade, Keshaum Houston, Melina Breaux, Elizabeth Secord

2024Journal of the Pediatric Infectious Diseases Society11 citationsDOI

Abstract

Nineteen youth living with HIV (YLWH) opted for injectable cabotegravir and rilpivirine without oral lead in and without achieving an undetectable HIV viral load (VL) for the 3 months prior to initiation. All achieved undetectable status within 3 months (3 injections) and maintained an undetectable status through 6-12 months of therapy.

Topics & Concepts

MedicineAntiretroviral therapyHuman immunodeficiency virus (HIV)Retrospective cohort studyANTIRETROVIRAL AGENTSViral loadVirologyIntensive care medicineInternal medicineHIV/AIDS drug development and treatmentHIV/AIDS Research and InterventionsPharmaceutical studies and practices
Off-label Use of Long-Acting Injectable Antiretroviral Therapy: A Single Center Retrospective Review of Youth Living With HIV With Detectable HIV RNA Starting Injectable Therapy | Litcius