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Unresolved Systemic Inflammation, Long COVID, and the Common Pathomechanisms of Somatic and Psychiatric Comorbidity

Chih‐Sung Liang, Piotr Gałecki, Kuan‐Pin Su

2022Journal of Clinical Medicine13 citationsDOIOpen Access PDF

Abstract

Monoamine hypothesis is an overestimated hypothesis of major depressive disorder (MDD), and the treatments and biomarkers that target it only show modest effect in randomized controlled trials+ (RCTs) or case-control studies [...].

Topics & Concepts

MedicineComorbidityMajor depressive disorderPsychiatric comorbidityCoronavirus disease 2019 (COVID-19)Randomized controlled trialSomatic cellPsychiatryInflammation2019-20 coronavirus outbreakSystemic inflammationInternal medicinePathologyMoodDiseaseGeneticsInfectious disease (medical specialty)OutbreakBiologyGeneTryptophan and brain disordersLong-Term Effects of COVID-19Stress Responses and Cortisol
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