In Situ Hexosomal Gel as a Promising Tool to Ameliorate the Transnasal Brain Delivery of Vinpocetine: Central Composite Optimization and In Vivo Biodistribution
Mohamed Mofreh Bakr, Marwa Hassan Shukr, Aliaa Nabil ElMeshad
Topics & Concepts
VinpocetineNasal administrationCmaxGellan gumPoloxamerBioavailabilityPharmacologyBiodistributionPharmacokineticsIn vivoChemistryChromatographyAnesthesiaBiomedical engineeringMedicineBiochemistryOrganic chemistryIn vitroBiologyFood scienceCopolymerPolymerBiotechnologyAdvanced Drug Delivery SystemsAlkaloids: synthesis and pharmacologyPhytochemistry and Biological Activities