Promotion of NAD+ recycling by the hypoxia-induced shift in the lactate dehydrogenase isozyme profile reduces the senescence of human bone marrow-derived endothelial progenitor cells
Kaihao Yan, Qiwei He, Dongni Lin, Jianli Liang, Junxiong Chen, Zijing Xie, Zhenzhou Chen
Topics & Concepts
SenescenceLactate dehydrogenaseNAD+ kinaseProgenitor cellMitophagyHypoxia (environmental)Bone marrowCell biologyChemistryIsozymeStem cellCancer researchBiologyBiochemistryApoptosisImmunologyEnzymeAutophagyOxygenOrganic chemistryCancer, Hypoxia, and MetabolismImmune cells in cancerMitochondrial Function and Pathology