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Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses

Vincent Wai‐Hin Yuen, David Kung‐Chun Chiu, Cheuk‐Ting Law, Jacinth Wing‐Sum Cheu, Cerise Yuen‐Ki Chan, Bowie Po‐Yee Wong, Chi Ching Goh, Misty Shuo Zhang, Helen Do-Gai Xue, Aki Pui‐Wah Tse, Yan Zhang, Henry Yee-Hin Lau, Derek Lee, Rex Au-Yeung, Chun‐Ming Wong, Carmen Chak‐Lui Wong, Carmen Chak‐Lui Wong, Carmen Chak‐Lui Wong

2022Journal of Hepatology62 citationsDOI

Topics & Concepts

HCCSCancer researchSorafenibCD8Hepatocellular carcinomaImmunotherapyImmune systemImmune checkpointBiologySomatic cellTumor microenvironmentMedicineImmunologyGeneticsGeneCRISPR and Genetic EngineeringCancer Immunotherapy and BiomarkersSingle-cell and spatial transcriptomics
Using mouse liver cancer models based on somatic genome editing to predict immune checkpoint inhibitor responses | Litcius