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Current-Reused Current Feedback Instrumentation Amplifier for Low Power Leadless Pacemakers

Gyuri Choi, Donggeun You, Hyunwoo Heo, Hyungseup Kim, Yongsu Kwon, Kyeongsik Nam, Sangmin Lee, Hyoungho Ko

2021IEEE Access16 citationsDOIOpen Access PDF

Abstract

This paper proposes a cardiac electrogram acquisition and stimulation integrated circuit (IC) for single-chamber leadless pacemaker applications. The proposed IC features self-determining pacing by acquiring an intracardiac electrogram without an external digital signal processor (DSP). A novel current-feedback instrumentation amplifier (CFIA) is proposed to achieve high noise-power efficiency and high input impedance. In this proposed CFIA, the current-reused cascode differential-difference input stage and class-AB biasing stage are merged. The electrocardiogram (ECG) sensing channel, equipped with a 60-Hz notch filter to relieve powerline interference (PLI), achieves a power supply rejection ratio (PSRR) of 80 dB, a common-mode rejection ratio (CMRR) of 174 dB, and an input-referred noise of 3.47 μVRMS, in a 350 Hz bandwidth. The ECG acquisition and cardiac pacing functionality of the IC are evaluated in a swine's right ventricle via a 4-electrode catheter.

Topics & Concepts

Common-mode rejection ratioInstrumentation amplifierCascodeElectronic engineeringElectrical engineeringComputer sciencePreamplifierOperational amplifierAmplifierEngineeringCMOSECG Monitoring and AnalysisAnalog and Mixed-Signal Circuit DesignNeuroscience and Neural Engineering
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