Enhancing the stability of active pharmaceutical ingredients by the cocrystal strategy
Liyu Liu, Jian‐Rong Wang, Xuefeng Mei
Abstract
Cocrystal strategies to achieve excellent physiochemical performance under different environmental stress were highlighted here. The lattice energy and the energy barrier of degradation reactions are two pillars in a stable cocrystal construction.
Topics & Concepts
CocrystalDegradation (telecommunications)Combinatorial chemistryChemistryLattice (music)Biochemical engineeringChemical engineeringMaterials scienceComputer scienceOrganic chemistryMoleculeEngineeringPhysicsTelecommunicationsHydrogen bondAcousticsCrystallography and molecular interactionsCrystallization and Solubility StudiesEnergetic Materials and Combustion