Targeting SIRT1, NLRP3 inflammasome, and Nrf2 signaling with chrysin alleviates the iron-triggered hepatotoxicity in rats
Samyah Alanazi, Samir A. Salama, Ahmed Elebiary, Abdulelah K. Altowairqi, Atheer T. Alharthi, Shahad M. Alzahrani, Shomokh H. Althagafi, Reema A. Alotaibi, Ahmed Abd-Eltawab Tammam
Topics & Concepts
ChrysinInflammasomePharmacologyChemistryIntraperitoneal injectionInflammationOxidative stressApoptosisAntioxidantInternal medicineMedicineEndocrinologyBiochemistryFlavonoidDrug-Induced Hepatotoxicity and ProtectionHeme Oxygenase-1 and Carbon MonoxideHemoglobinopathies and Related Disorders