Litcius/Paper detail

Base-editing mutagenesis maps alleles to tune human T cell functions

Ralf Schmidt, Carl C. Ward, Rama Dajani, Zev Armour-Garb, Mineto Ota, Vincent Allain, Rosmely Hernandez, Madeline Layeghi, Galen Xing, Laine Goudy, Dmytro Dorovskyi, Charlotte Wang, Yan Yi Chen, Chun Ye, Brian R. Shy, Luke A. Gilbert, Justin Eyquem, Jonathan K. Pritchard, Stacie E. Dodgson, Alexander Marson

2023Nature94 citationsDOIOpen Access PDF

Topics & Concepts

MutagenesisGeneBiologyComputational biologyGeneticsCRISPRFunction (biology)Genome editingPhenotypeMutationCRISPR and Genetic EngineeringCAR-T cell therapy researchCytomegalovirus and herpesvirus research