Litcius/Paper detail

Candida auris, an emerging pathogen – Challenge in the survival of microprimies

Gurujala Mahadeva Ramya, Umamaheswari Balakrishnan, Ashok Chandrasekaran, Thangaraj Abiramalatha, Prakash Amboiram, Uma Sekar, R. UshaDevi

2021Indian Journal of Medical Microbiology38 citationsDOIOpen Access PDF

Abstract

Clinical profile of extreme preterm neonates and more so, of microprimies with birth weight < 800 g is not studied till now. Our article elaborates the profile of 5 microprimies with C.auris sepsis and review of literature. The mean gestational age and birth weight were 26 weeks ± 5 days and 709 ± 64 g respectively. Mortality was 80%. The organism was susceptible to micafungin, voriconazole but was resistant to fluconazole and amphotericin. Among the 5 babies, one had organ involvement in the form of cardiac vegetation. Early identification and optimal choice of drug are crucial for better survival in C.auris sepsis.

Topics & Concepts

Candida aurisFluconazoleVoriconazoleMicafunginFungal pathogenSepsisPathogenLow birth weightBirth weightAmphotericin BMedicineInternal medicineBiologyAntifungalMicrobiologyPregnancyGeneticsAntifungal resistance and susceptibilityNeonatal and Maternal InfectionsPneumonia and Respiratory Infections