PEG-Neridronate-Modified NaYF<sub>4</sub>:Gd<sup>3+</sup>,Yb<sup>3+</sup>,Tm<sup>3+</sup>/NaGdF<sub>4</sub> Core–Shell Upconverting Nanoparticles for Bimodal Magnetic Resonance/Optical Luminescence Imaging
Uliana Kostiv, Marta Maria Natile, Daniel Jirák, Denisa Půlpánová, Klára Jiráková, Magda Vosmanská, Daniel Horák
Abstract
relaxivities of PEG-Ner-modified nanoparticles were much higher compared to those of non-PEGylated particles, thus manifesting their potential as a diagnostic tool for magnetic resonance imaging. Together with the enhanced luminescence efficiency, upconverting nanoparticles might represent an efficient probe for bimodal in vitro and in vivo imaging of cells in regenerative medicine, drug delivery, and/or photodynamic therapy.
Topics & Concepts
NanoparticleMaterials scienceEthylene glycolGadoliniumLuminescencePEG ratioNanotechnologyAnalytical Chemistry (journal)ChemistryOrganic chemistryOptoelectronicsMetallurgyEconomicsFinanceLuminescence Properties of Advanced MaterialsNanoplatforms for cancer theranosticsInorganic Fluorides and Related Compounds