BRCA1 protects cardiac microvascular endothelial cells against irradiation by regulating p21-mediated cell cycle arrest
Zhimin Zeng, Haiyang Du, Le Xiong, Xiao-li Zeng, Peng Zhang, Jing Cai, Long Huang, Anwen Liu
Topics & Concepts
Cell cycleEndothelial stem cellCell cycle checkpointDNA damageGene knockdownCell biologyCancer researchCell growthApoptosisCyclin ABiologyCyclin D1In vitroBiochemistryDNAEffects of Radiation ExposureDNA Repair MechanismsPARP inhibition in cancer therapy