Litcius/Paper detail

High-Dose Acetaminophen with Concurrent CYP2E1 Inhibition Has Profound Anticancer Activity without Liver Toxicity

Allyn Bryan, Pavani Pingali, Anthony C. Faber, Joseph W. Landry, Jephte Y. Akakpo, Hartmut Jaeschke, Howard Li, Won Sok Lee, Lauren May, Bhaumik B. Patel, Alex Neuwelt

2023Journal of Pharmacology and Experimental Therapeutics11 citationsDOIOpen Access PDF

Topics & Concepts

PharmacologyToxicityAcetaminophenMedicineCYP2E1In vivoMetaboliteChemistryMetabolismInternal medicineCytochrome P450BiologyBiotechnologyPharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and ProtectionEicosanoids and Hypertension Pharmacology