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Antiviral Activity Exerted by Natural Products against Human Viruses

Maria Musarra‐Pizzo, Rosamaria Pennisi, Ichrak Ben Amor, Giuseppina Mandalari, Maria Teresa Sciortino

2021Viruses148 citationsDOIOpen Access PDF

Abstract

Viral infections are responsible for several chronic and acute diseases in both humans and animals. Despite the incredible progress in human medicine, several viral diseases, such as acquired immunodeficiency syndrome, respiratory syndromes, and hepatitis, are still associated with high morbidity and mortality rates in humans. Natural products from plants or other organisms are a rich source of structurally novel chemical compounds including antivirals. Indeed, in traditional medicine, many pathological conditions have been treated using plant-derived medicines. Thus, the identification of novel alternative antiviral agents is of critical importance. In this review, we summarize novel phytochemicals with antiviral activity against human viruses and their potential application in treating or preventing viral disease.

Topics & Concepts

Antiviral drugDiseaseVirologyBiologyViral hepatitisViral diseaseHuman pathogenHuman immunodeficiency virus (HIV)Human diseaseMedicineVirusImmunologyPathologyGeneticsBacteriaViral gastroenteritis research and epidemiologySARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies
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