Litcius/Paper detail

High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease 2019

Wei Cao, Xiaosheng Liu, Tao Bai, Hongwei Fan, Ke Hong, Hui Song, Yang Han, Ling Lin, Lianguo Ruan, Taisheng Li

2020Open Forum Infectious Diseases418 citationsDOIOpen Access PDF

Abstract

The outbreak of coronavirus disease 2019 (COVID-19) has spread rapidly in China. Until now, no definite effective treatment has been identified. We reported on 3 patients with severe COVID-19 who received high-dose intravenous immunoglobulin (IVIg) with satisfactory recovery. Based on these observations, randomized studies of high-dose IVIg should be considered in deteriorating patients infected with COVID-19.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)AntibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Outbreak2019-20 coronavirus outbreakCoronavirusDiseaseIntravenous ImmunoglobulinsInternal medicineImmunologyVirologyInfectious disease (medical specialty)COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19