Pirfenidone ameliorates ANIT-induced cholestatic liver injury via modulation of FXR, NF-кB/TNF-α, and Wnt/GSK-3β/β-catenin signaling pathways
Wesam H. Abdulaal, Ulfat M. Omar, Mustafa Zeyadi, Dina S. El‐Agamy, Nabil A. Alhakamy, Sabrin R. M. Ibrahim, Naif A. R. Almalki, Hani Z. Asfour, Mohammed W. Al-Rabia, Gamal A. Mohamed, Mahmoud Elshal
Topics & Concepts
Wnt signaling pathwayNF-κBPirfenidoneLiver injuryChemistryTumor necrosis factor alphaCateninSignal transductionBeta-cateninCancer researchPharmacologyMedicineInternal medicineBiochemistryLungIdiopathic pulmonary fibrosisLiver Disease Diagnosis and TreatmentLiver Disease and TransplantationDrug-Induced Hepatotoxicity and Protection