ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation
Tianliang Sun, Stefano Annunziato, Sebastian Bergling, Caibin Sheng, Vanessa Orsini, Pascal Forcella, Monika Pikiolek, Venkatesh Kancherla, Sjoerd J.B. Holwerda, Dilek Imanci, Fabian Wu, Ludivine Challet Meylan, Lea F. Puehringer, Annick Waldt, Mevion Oertli, Sven Schuierer, Luigi Terracciano, Stefan Reinker, Heinz Ruffner, Tewis Bouwmeester, Andreas W. Sailer, Elizabeth George, Guglielmo Roma, Antoine de Weck, Salvatore Piscuoglio, Felix Lohmann, Ulrike Naumann, Prisca Liberali, Feng Cong, Jan S. Tchorz
Topics & Concepts
BiologyWnt signaling pathwayAXIN2HepatocyteCell biologyLGR5Stem cellLiver regenerationDownregulation and upregulationCancer researchSignal transductionGeneticsRegeneration (biology)GeneIn vitroLiver physiology and pathologyEpigenetics and DNA MethylationWnt/β-catenin signaling in development and cancer