Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators
Chih Hung Lo, Tory Schaaf, David D. Thomas, Jonathan N. Sachs
Topics & Concepts
Förster resonance energy transferAllosteric regulationBiosensorReceptorSmall moleculeBiophysicsTumor necrosis factor receptor 1ChemistryHigh-throughput screeningDrug discoveryFluorescenceNanotechnologyCell biologyBiochemistryBiologyMaterials scienceTumor necrosis factor receptorPhysicsQuantum mechanicsReceptor Mechanisms and SignalingImmune Response and InflammationViral Infectious Diseases and Gene Expression in Insects