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Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysis

Cheng‐Wei Yang, Hsing‐Yu Hsu, Hsin-Yu Chang, Yue‐Zhi Lee, Shiow‐Ju Lee

2020Biochemical Pharmacology22 citationsDOIOpen Access PDF

Topics & Concepts

ProteolysisEffectorCell biologyInfectivityBiologyATPaseGene silencingChemistryVirologyBiochemistryGeneVirusEnzymeinterferon and immune responsesImmune Cell Function and InteractionNF-κB Signaling Pathways
Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysis | Litcius