FAM72A promotes glioma progression by regulating mitophagy through the Pink1/Parkin signaling pathway
Yibin Zeng, Cui Xiong, Nan Tang, Siqi Wang, Zhiyong Xiong, Tao Liang, Qiangping Wang, Menglong Li, Junjun Li
Abstract
All of these data indicate that FAM72A confers an aggressive phenotype and poor prognosis on gliomas. Targeting FAM72A might represent a new therapeutic strategy for glioma.
Topics & Concepts
ParkinGliomaMitophagyPINK1Cancer researchDownregulation and upregulationSignal transductionPhenotypeBlotBiologyCell biologyMedicineApoptosisParkinson's diseasePathologyGeneticsGeneAutophagyDiseaseAutophagy in Disease and TherapyHistone Deacetylase Inhibitors ResearchGlioma Diagnosis and Treatment